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SYNTHESIS AND PHOTOSENSITIZING ACTIVITY OF A DI‐PORPHYRIN ETHER
Author(s) -
Pandey Ravindra K.,
Dougherty Thomas J.
Publication year - 1988
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1988.tb01658.x
Subject(s) - porphyrin , photosensitizer , dimer , ether , chemistry , in vivo , nuclear magnetic resonance spectroscopy , stereochemistry , proton nmr , dimethyl ether , photochemistry , organic chemistry , catalysis , biology , microbiology and biotechnology
A simple, well characterized porphyrin dimer with ether linkage was synthesized from 2‐ (1‐hydroxyethyl)deuteroporphyrin dimethyl ester and found to be an effective in vivo photosensitizer in the murine SMT‐F tumor system. The structure of the pure dimer was confirmed by NMR and mass spectroscopy.