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OVERVIEW OF EXPERIENCES WITH PHOTODYNAMIC THERAPY FOR MALIGNANCY IN 192 PATIENTS
Author(s) -
McCaughan James S.
Publication year - 1987
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1987.tb04867.x
Subject(s) - hematoporphyrin , photodynamic therapy , light source , malignancy , laser light , medicine , laser therapy , ether , dye laser , dermatology , laser , chemistry , optics , physics , organic chemistry
From April 1982 to April 1986 we used photodynamic therapy to treat 192 patients with various malignancies. In all, 172 injections of hematoporphyrin derivative and 135 injections of dihematoporphyrin ether were made intravenously to sensitize the tumors; 684 photodynamic treatments were given using a tunable dye argon laser system for the light source. The technical problems of the light source and delivery systems are presented and the efficacy of therapy is analyzed.