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INHIBITION OF NUCLEIC ACID SYNTHESIS IN CELLS EXPOSED TO 200 MICROMETER RADIATION FROM THE FREE ELECTRON LASER
Author(s) -
Berns Michael W.,
Bewley William
Publication year - 1987
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1987.tb04752.x
Subject(s) - laser , nucleic acid , radiation , free electron laser , micrometer , dna , biophysics , wavelength , chemistry , dna synthesis , optics , biology , biochemistry , physics
Vertebrate tissue culture cells were exposed to 200 um wavelength radiation (1CO W/cm 2 ) from a free electron laser (FEL) of the electrostatic generator type. Cell cultures demonstrated no morphological alterations but a statistically significant (P .05) proportion of the cells exhibited inhibition of DNA synthesis. This study demonstrates the first biological effects of the FEL and the feasibility of performing biological investigations with this device.