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CHLORPROMAZINE INGESTION INHIBITS UV‐INDUCED SKIN CARCINOGENESIS
Author(s) -
Peak Meyrick J.,
Pfaff Michelle M.,
Peraino Carl
Publication year - 1987
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1987.tb04728.x
Subject(s) - hairless , chlorpromazine , ingestion , carcinogenesis , chemistry , irradiation , pharmacology , skin cancer , cancer , medicine , biochemistry , physics , nuclear physics , gene
Chlorpromazine (0.01% in drinking water) inhibits the induction of skin cancer by sunlamp irradiation of hairless mice. This inhibition is partially reversed by a single injection of ethyl nitrosourea at birth.