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THE PHOTOPHYSICAL PROPERTIES OF PORPHYCENES: POTENTIAL PHOTODYNAMIC THERAPY AGENTS *
Author(s) -
Aramendia Pedro F.,
Redmond Robert W.,
ll Santiago,
Schuster Wolfang,
Braslavsky Silvia E.,
Schaffner Kurt,
Vogel Emanuel
Publication year - 1986
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1986.tb04708.x
Subject(s) - singlet oxygen , photochemistry , intersystem crossing , porphyrin , chemistry , photodynamic therapy , singlet state , fluorescence , sensitization , phosphorescence , derivative (finance) , absorption (acoustics) , excited state , oxygen , materials science , organic chemistry , medicine , physics , nuclear physics , financial economics , economics , immunology , composite material , quantum mechanics
Porphycene and a tetra‐n‐propyl derivative remained unaltered on irradiation in toluene at room temperature. Quantum yields of fluorescence, S T intersystem crossing, and singlet molecular oxygen sensitization, as well as lifetimes of the singlet and triplet excited states were measured. In view of their structural relationship to porphyrin, their high absorption above 620 nm, their stability towards photooxidation, and their high quantum yields of fluorescence and singlet oxygen sensitization, these compounds qualify as potential agents for tumor marking and photodynamic therapy.