Premium
INDUCTION OF SISTER‐CHROMATID EXCHANGES IN ICR 2A FROG CELLS EXPOSED TO 254 NM AND SOLAR UV WAVELENGTHS
Author(s) -
Chao Chuck C.K.,
Rosenstein Barry S.
Publication year - 1985
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1985.tb03537.x
Subject(s) - sister chromatids , chemistry , fluence , sunlight , biophysics , fluorescence , wavelength , photochemistry , optics , biology , physics , ion , biochemistry , chromosome , gene , organic chemistry
— Exposure of ICR 2A frog cells to 254 nm UV induced the formation of sister‐chromatid exchanges (SCEs) in a fluence‐dependent manner. Cells were also exposed to the UV produced by a fluorescent sunlamp that was filtered through 8C Mylar in order to simulate the mid‐UV(290–320 nm) portion of sunlight reaching the earth's surface. In this instance, SCEs were induced in a linear fashion at low fluences but reached a plateau at a low level of induced SCEs. In addition, pretreatment of cells with the solar UV followed by exposure to 254 nm UV resulted in a significantly lower level of SCEs than in cells exposed to 254 nm UV alone.