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ACTION SPECTRA (254–302 nm) FOR FOUR HUMAN PHOTOSENSITIVE CELL LINES
Author(s) -
Coohill Thomas P.,
Moore Sharon P.,
Grider Rebecca A.
Publication year - 1983
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1983.tb08373.x
Subject(s) - xeroderma pigmentosum , cockayne syndrome , cell culture , fibroblast , action spectrum , microbiology and biotechnology , biology , wavelength , chemistry , genetics , biophysics , optics , dna repair , physics , dna
— The inactivation of cellular viral capacity for Herpes simplex type I growth at six separate wavelengths (254–302 nm) was measured in five human cell lines. These consisted of one “normal” skin fibroblast line (KD), and four photosensitive lines. Two lines of Xeroderma pigmentosum, one of Bloom's syndrome, and one of Cockayne's syndrome cells were used. Similar relative sensitivities were observed for the Bloom's syndrome, Xeroderma pigmentosum, and normal cell lines. The Cockayne's syndrome line became relatively more sensitive at 289 nm and longer wavelengths. Absolute sensitivities varied. Some divergence in response was noted at the longest wavelength tested, 302 nm.