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PRIOR EXPOSURE OF HUMAN CELLS TO NEAR UV‐RADIATION GIVES A DECREASE IN THE AMOUNT OF THE UNSCHEDULED DNA‐SYNTHESIS INDUCED BY FAR UV‐RADIATION
Author(s) -
Holmberg M.
Publication year - 1983
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1983.tb04475.x
Subject(s) - noon , radiation , sunlight , irradiation , ultraviolet radiation , background radiation , dna , radiation exposure , chemistry , optics , physics , radiochemistry , astronomy , biochemistry , medicine , nuclear medicine , nuclear physics
Pretreatment of human cells with near UV radiation (UVA) in fluences exceeding 5 × 10 4 Jm −2 caused a decrease in the amount of the unscheduled DNA synthesis induced by far UV radiation (UVC). The DNA repair synthesis, as measured by the incorporation of [ 3 H] ‐thymidine, is reduced by nearly a factor of 2 for a UVA radiation exposure of 1.5 × 10 5 Jm −2 . Since solar UVA fluence rate is rather independent of latitude, this figure corresponds to a UVA exposure time of 50‐60 min from noon sunlight in the summer time.