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HYPOCALCEMIA ASSOCIATED WITH PHOTOTHERAPY IN NEWBORN RATS: LIGHT SOURCE DEPENDENCE
Author(s) -
Gutcher Gary R.,
Odell Gerard B.
Publication year - 1983
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1983.tb04455.x
Subject(s) - bilirubin , hematocrit , calcium , medicine , endocrinology , chemistry , serum bilirubin , irradiation , daylight , physics , nuclear physics , optics
Littermate pups of the congenitally jaundiced Gunn rat were studied at 4 days of age. Control animals were shaded from irradiation by opaque cardboard while littermates were exposed to daylight, blue, green or pink fluorescent light. Initially no significant differences were demonstrable between irradiated and control animals with reference to body weight, sex distribution, blood hematocrit, or serum bilirubin and serum calcium concentration. In all control groups, serum bilirubin values were unchanged or increased by the end of the study and serum calcium values were also unchanged. In the light‐exposed groups, serum bilirubin values decreased significantly in all except those exposed to pink light. The serum calcium level was decreased significantly only in pups exposed to fluorescent daylight at 5.00 μW/cm 2 /nm but in none of the other irradiated groups.