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1 H AND 13 C PHOTO‐CIDNP STUDY OF AQUEOUS CHLORPROMAZINE AND ANALOGS*
Author(s) -
Marko J.,
Vermeersch G.,
FebvayGarot N.,
Caplain S.,
LablacheComboer A.
Publication year - 1983
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1983.tb03858.x
Subject(s) - cidnp , chemistry , aqueous solution , carbon atom , solvent , photochemistry , ion , chlorpromazine , cleavage (geology) , aqueous medium , derivative (finance) , medicinal chemistry , stereochemistry , polarization (electrochemistry) , alkyl , organic chemistry , materials science , medicine , fracture (geology) , financial economics , economics , composite material , endocrinology
— The photochemical reaction in aqueous solutions of several phenothiazines with an N‐alkylamine chain, and their salts, is studied by means of Chemically Induced Dynamic Nuclear Polarization (CIDNP) ¶ . The particular behaviour of chlorpromazine hydrochloride is outlined and evidence is shown for the existence of a substitution product with the solvent at the α‐carbon atom of the side‐chain, and an aldehydic derivative resulting in the cleavage of that one. Radical‐ions pairs of CPZ are involved in both processes.