HYDRODYNAMIC EFFECTS IN THE PHOTOSENSITIZED LYSIS OF LIPOSOMES * | Zendy

Grossweiner Leonard I. | Zendy; Grossweiner James B. | Zendy

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HYDRODYNAMIC EFFECTS IN THE PHOTOSENSITIZED LYSIS OF LIPOSOMES *

Author(s) -

Grossweiner Leonard I.,

Grossweiner James B.

Publication year - 1982

Publication title -

photochemistry and photobiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.818

H-Index - 131

eISSN - 1751-1097

pISSN - 0031-8655

DOI - 10.1111/j.1751-1097.1982.tb02614.x

Subject(s) - methylene blue , liposome , lysis , singlet oxygen , chemistry , phosphatidylcholine , membrane , photochemistry , biophysics , methylene , oxygen , biochemistry , organic chemistry , phospholipid , biology , catalysis , photocatalysis

— The photosensitized lysis of phosphatidylcholine liposomes incorporating methylene blue in the membrane or in the presence of external methylene blue is promoted by hydrodynamic agitation concurrent with or subsequent to irradiation with red light. The results implicate the attack of singlet oxygen on an unsaturated lipid component as the key photochemical step, which is followed by additional membrane damage induced by hydrodynamic action.

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