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A SECOND PHOTOREACTIVATION‐DEFICIENT MUTATION IN SACCHAROMYCES CEREVISIAE
Author(s) -
MacQuillan Anthony M.,
Herman Andrew,
Coberly Jacqueline S.,
Green Gisele
Publication year - 1981
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1981.tb09062.x
Subject(s) - photolyase , saccharomyces cerevisiae , genetics , mutation , saccharomyces , biology , dna repair , yeast , dna , gene
— A mutant of Saccharomyces cerevisiae was isolated which has a low capability for photoreactivating UV‐induced lethal damage. The DNA photolyase activity of the cell‐free extract is much less than in a wild‐type strain. In vivo complementation of photoreactivation was demonstrated in crosses with phr1 mutant strains. Tetrad analysis and backcrosses suggest that this new mutation defines a second chromosomal gene PHR2 which is loosely linked to the PHR1 gene.