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THE WAVELENGTH DEPENDENCE OF HERPES SIMPLEX VIRUS INACTIVATION BY ULTRAVIOLET RADIATION
Author(s) -
Detsch Richard M.,
Bryant F. Dudley,
Coohill Thomas P.
Publication year - 1980
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1980.tb04005.x
Subject(s) - wavelength , ultraviolet , action spectrum , herpes simplex virus , ultraviolet radiation , radiation , chemistry , nucleic acid , virus , absorption (acoustics) , virology , biophysics , optoelectronics , biology , materials science , optics , physics , photochemistry , biochemistry , radiochemistry
— The effect of different wavelengths of ultraviolet (UV) radiation on Herpes simplex virus when assayed on mammalian cells (measured by plaque forming ability) was investigated. The wavelength dependence of viral inactivation was obtained for 11 different wavelengths over the region 238–297 nm. The resulting action spectrum does not closely follow the absorption spectrum of either nucleic acid or protein. The most effective wavelengths for viral inactivation are over the region 260–280 nm.