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HERPES SIMPLEX VIRUS PRODUCES LARGER PLAQUES WHEN ASSAYED ON ULTRAVIOLET IRRADIATED CV1 CELLS
Author(s) -
Coohill Thomas P.,
Babich Michael A.,
Taylor William D.,
Snipes Wallace
Publication year - 1980
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1980.tb03992.x
Subject(s) - herpes simplex virus , irradiation , virus , ultraviolet irradiation , cell , inoculation , virology , ultraviolet , biology , chemistry , immunology , physics , optics , biochemistry , nuclear physics
— Plaque development for either untreated or UV treated irradiated Herpes simplex virus Type 1 is faster when assayed on UV irradiated CV1 cells. This Large Plaque Effect only occurs if a minimum delay of 12h between cell irradiation and viral inoculation is allowed. Shorter delays give plaques that are smaller than controls (unirradiated virus‐unirradiated cells). The effect is maximal for a 48‐h delay and remains unchanged for delays as long as 84h. The effect is greatest for cell exposures of 10J m ‐2 .