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ENHANCED KILLING OF CHINESE HAMSTER CELLS FOLLOWING COMBINED EXPOSURE TO ‘SUNLIGHT’ AND X‐RAYS*
Author(s) -
Han A.,
Elkind M. M.
Publication year - 1980
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1980.tb03719.x
Subject(s) - sunlight , chinese hamster , dna damage , biophysics , chemistry , irradiation , dna , optics , biology , physics , biochemistry , nuclear physics
— Enhanced cell killing due to combined exposure to sunlight‐like near‐UV light (Westinghouse Sun Lamps, FS20) and X‐rays, indicative of damage interaction, is observed at all stages of the cell cycle. The greatest interaction is observed in the middle of the DNA synthetic phase. At equal survival, ‘sunlight’ damage is only partly additive to X‐ray damage, and vice versa , whereas in earlier studies we found that far‐UV light (254 nm) produces damage completely additive to X‐ray damage. Loss of damage interaction between radiations is more rapid after a first dose of X‐rays than after a first dose of ‘sunlight’.