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PHOTOCHEMICAL REACTIONS BETWEEN TRYPTOPHAN AND POLYNUCLEOTIDES *
Author(s) -
Reeve A. E.,
Hopkins T. R.
Publication year - 1980
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1980.tb02561.x
Subject(s) - polynucleotide , tryptophan , chemistry , adduct , ribonuclease , trichloroacetic acid , hydrolysis , irradiation , pancreatic ribonuclease , photochemistry , acid hydrolysis , biochemistry , organic chemistry , amino acid , rna , physics , nuclear physics , gene
— Anaerobic solutions of 14 C labelled tryptophan and single‐stranded synthetic polyribonucleotide form adducts when irradiated with UV light at wavelengths longer than 270 nm. These adducts are stable to cold 10% trichloroacetic acid and are also more resistant to hydrolysis catalyzed by bovine ribonuclease A than non‐irradiated controls. All polyribonucleotides reacted with trp to some extent with reactivities in the order poly rU > poly rC = poly rA > poly rG.