Premium
PHOTOSENSITIZED CYCLODIMERIZATION OF 5‐FLUOROURACIL
Author(s) -
Shim Sang Chul,
Lee Seung Han
Publication year - 1979
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1979.tb07810.x
Subject(s) - dimer , chemistry , yield (engineering) , acetone , aqueous solution , quantum yield , fluorouracil , proton nmr , nmr spectra database , spectral line , photochemistry , stereochemistry , organic chemistry , materials science , physics , fluorescence , optics , medicine , surgery , chemotherapy , astronomy , metallurgy
—The photosensitization by acetone or N‐methyllutidone yields a C 4 ‐cyclodimer from 5‐fluorouracil in aqueous solution. with a quantum yield of 2 × 10 ‐ ‐ 3 . The dimer isolated has been characterized by UV, IR. NMR, and mass spectra. The stereochemistry of the dimer has been determined to be anti head‐to‐tail configuration from the NMR spectral analysis.