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THE EFFECT OF DNA BINDING ON INITIAL 8‐METHOXYPSORALEN PHOTOCHEMISTRY *
Author(s) -
Goyal Greesh C.,
Grossweiner L. I.
Publication year - 1979
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1979.tb07777.x
Subject(s) - psoralen , singlet oxygen , photochemistry , chemistry , quenching (fluorescence) , flash photolysis , dna , biophysics , oxygen , triplet state , anaerobic exercise , kinetics , biochemistry , fluorescence , biology , molecule , reaction rate constant , organic chemistry , physics , quantum mechanics , physiology
—Flash photolysis experiments on the complex of 8‐methoxypsoralen with calf thymus DNA have shown binding promotes the anaerobic quenching of the 8‐MOP triplet state and inhibits the accessibility to oxygen. The results indicate dark psoralen‐DNA interactions suppress the singlet oxygen generation observed in prior work.