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DAMAGE TO THE ALBINO RAT RETINA PRODUCED BY LOW INTENSITY LIGHT *
Author(s) -
Rapp L. M.,
Williams T. P.
Publication year - 1979
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1979.tb07758.x
Subject(s) - retina , rhodopsin , erg , adaptation (eye) , light intensity , intensity (physics) , biophysics , biology , electroretinography , anatomy , chemistry , optics , retinal , neuroscience , physics , biochemistry
—Continuous exposure of albino rats to low intensity light causes progressive deterioration of the photoreceptor cells. Losses in ERG (b‐wave) sensitivity which accompany this ‘light damage’ are directly related to lowered rhodopsin levels in the retina. The same relationship has been observed in light adaptation studies in which the retina is not damaged. Thus, it appears that the production of b‐wave responses is not seriously altered when photoreceptor morphology is disrupted.