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THE OXIDATION OF CHOLESTEROL BY HYDROXYL RADICAL
Author(s) -
Ansari G. A. S.,
Smith Leland L.
Publication year - 1979
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1979.tb07127.x
Subject(s) - radiolysis , chemistry , sterol , triol , hydroxyl radical , cholesterol , epoxy , aqueous solution , radical , organic chemistry , oxygen , photochemistry , diol , biochemistry
— The oxidation of chblesterol by hydroxyl radical generated by 60 Co y‐radiolysis of aqueous cholesterol dispersions or of dispersions saturated with N 2 O ave in low yields the products 38‐hydroxy‐cholest‐5‐en‐7‐one. the epimeric cholest‐5‐ene‐3β,7‐diols, 5,6α‐epoxy‐5α‐cholestan‐3β‐ol, 5.6β‐epoxy‐5β‐cholestan‐3,β‐ol, and 5α‐cholestane‐38,5,6β‐triol. Sterol hydroperoxides were not detected except in the radiolysis of dispersions saturated with oxygen.