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OCCURRENCE OF PYRIMIDINE‐RICH TRACTS IN ASCITES TUMOR DNA AND THE FORMATION OF UV‐INDUCED THYMINE DIMERS
Author(s) -
Ramakrishnan Narayani,
Pradhan D. S.
Publication year - 1979
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1979.tb07087.x
Subject(s) - pyrimidine dimer , thymine , pyrimidine , dna , ascites , chemistry , biology , microbiology and biotechnology , biochemistry , biophysics , dna damage , medicine
— Analysis of the distribution of pyrimidine‐rich tracts (up to decanucleotides) in ascites tumor DNA revealed that these tracts occur predominantly in repetitive sequence of DNA. UV irradiation of ascites DNA resulted in preferential formation of thymine dimers in the pyrimidine‐rich tracts as compared to other regions of DNA.