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ROLE OF DYE MOLECULES REMAINING OUTSIDE THE CELL DURING PHOTODYNAMIC INACTIVATION OF ESCHERICHIA COLI IN THE PRESENCE OF ACRIFLAVINE
Author(s) -
Bagchi B.,
Basu Sreeradha
Publication year - 1979
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1979.tb07067.x
Subject(s) - acriflavine , singlet oxygen , chemistry , escherichia coli , biophysics , photochemistry , photodynamic therapy , photosensitizer , oxygen , biochemistry , biology , organic chemistry , gene
— Photodynamic inactivation of cells is caused by damage to the regions proximal to the cell envelope or to the DNA via a singlet oxygen mechanism. For penetrating dyes the possibility of either type of damage remains. The contribution of a penetrating dye. acriflavine. remaining outside E. coli B/r cells during irradiation. towards photodynamic inactivation was investigated. It was found that this contribution was either nil or negligible.