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CYTIDINE‐C(5)‐PHOTOEXCHANGE: A KINETIC ANALYSIS*
Author(s) -
Hauswirth William,
Wang Shih Yi
Publication year - 1977
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1977.tb07478.x
Subject(s) - cytidine , kinetics , tritium , chemistry , kinetic energy , photochemistry , physics , biochemistry , enzyme , nuclear physics , quantum mechanics
. –The kinetics of photolytic tritium exchange at C(5) of [5‐T]cytidine are analyzed in terms of the rate of cytidine light absorption in order to demonstrate its light‐induced nature as opposed to spontaneous exchange from a stable photoproduct. Corrections must be included for an inner filter effect and a spontaneous C(5)‐tritium exchange both due to cytidine photohydrate produced during UV exposure. The quantum efficiency of this C(5)‐photoexchange process is of the same order of magnitude as that for cytidine photohydration.