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A NEW FACET IN RHODOPSIN PHOTOCHEMISTRY
Author(s) -
Meer K. van der,
Mulder J. J. C.,
Lugtenburg J.
Publication year - 1976
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1976.tb06837.x
Subject(s) - rhodopsin , opsin , tautomer , visual pigments , chemistry , absorption (acoustics) , photochemistry , retinal , pigment , absorption spectroscopy , raman spectroscopy , facet (psychology) , group (periodic table) , stereochemistry , optics , physics , organic chemistry , biochemistry , psychology , social psychology , personality , big five personality traits
— A structure is proposed for the prosthetic group of the visual pigments rhodopsin, prelumirhodopsin (bathorhodopsin) and lumirhodopsin. The intrinsic photochemical step in this model is tautomerization of the prosthetic group of rhodopsin to a hexaeneamine retrotautomer with an exomethylene group for prelumirhodopsin. Based on the proposed structures, molecular orbital calculations were carried out; the absorption maxima calculated snowed the same trends as the Λ max values observed. An exact fit was not obtained because many interactions had to be neglected. Essential information of the laser Raman resonance spectrum of prelumirhodopsin can be interpreted based on the structures proposed by our model. The model elucidates why some retinal derivates can and others cannot form visual pigments with opsin and visual pigments having vastly differing absorption maxima yet employ the same mechanism for their photoreaction.