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INTERACTION OF DISULFIDE GROUPS WITH NUCLEIC ACID BASES
Author(s) -
MontenayGarestier Thérèse,
Brun Francine,
Hélène Claude
Publication year - 1976
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1976.tb06778.x
Subject(s) - cystamine , chemistry , nucleic acid , quenching (fluorescence) , cysteine , fluorescence , photochemistry , combinatorial chemistry , organic chemistry , biochemistry , enzyme , physics , quantum mechanics
— Low temperature luminescence studies have provided evidence for interactions between the disulfide group of cystamine and adenine bases in cystamine‐poly(A) complexes and in cystamine‐adenosine aggregates. A quenching of adenine phosphorescence by cystamine was observed. At room temperature complex formation between cystamine and poly(A) was followed by proton magnetic resonance, absorption spectrophotometry and fluorescence using competition with a fluorescent peptide to monitor the binding process. These base‐disulfide interactions could be involved in the photochemistry of protein‐nucleic acid complexes.