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PHYTOENE AS A PROTECTIVE AGENT AGAINST SUNBURN (>280nm) RADIATION IN GUINEA PIGS
Author(s) -
MathewsRoth Micheline M.,
Pathak Madhu A.
Publication year - 1975
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1975.tb06666.x
Subject(s) - erythema , phytoene , placebo , sunburn , body weight , intraperitoneal injection , pharmacology , medicine , chemistry , food science , zoology , dermatology , carotenoid , biology , lycopene , pathology , alternative medicine
— Phytoene, the colorless triene precursor of β‐carotene (17 mg/g body weight) or a placebo was given to guinea pigs by daily intraperitoneal injection for 14 days, after which the animals were exposed to radiation (> 280 nm). It was found that the animals receiving phytoene developed significantly less erythema to the radiation than did the animals receiving placebo.