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EPIDERMAL HYPERPLASIA INDUCED BY ULTRAVIOLET RADIATION; ERROR AND UNCERTAINTY OF MEASUREMENT *
Author(s) -
Blum Harold F.,
McVaugh Julia,
Ward Margery,
Bush Harry L.
Publication year - 1975
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1975.tb06665.x
Subject(s) - photolyase , hyperplasia , epidermis (zoology) , ultraviolet radiation , population , cell , chemistry , biology , medicine , biochemistry , endocrinology , anatomy , radiochemistry , environmental health , dna repair , gene
— Measurements of epidermal hyperplasia induced by UV in albino mice, using an improved method of sampling and counting of cells, show wide variability attributable largely to basic uncertainty rather than experimental error. Factors are analyzed that may contribute to the infeasibility of determining simultaneously the size of cell population and rate of cell duplication, including recovery of cell activity enhanced by photoreactivation. A hyperplasia‐inducing factor is isolated from epidermis exposed to UV.