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PHOTODYNAMIC INACTIVATION OF SARCOPLASMIC RETICULUM VESICLE MEMBRANES BY XANTHENE DYES
Author(s) -
Kondo Mitsuo,
Kasai Michiki
Publication year - 1974
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1974.tb06471.x
Subject(s) - xanthene , chemistry , absorbance , vesicle , membrane , fluorescence , photochemistry , endoplasmic reticulum , calcium , atpase , biophysics , biochemistry , chromatography , organic chemistry , biology , physics , quantum mechanics , enzyme
— Photosensitized oxidation of sarcoplasmic reticulum (SR) vesicle membranes by a series of xanthene dyes was investigated. With increasing dye concentration and illumination time, the calcium ion uptake, ATPase activity and UV fluorescence intensity of SR decreased, and the absorbance at 241 nm increased. In xanthene dyes, the order of inactivation of the calcium uptake and ATPase activity of SR was in accord with decreasing order, of fluorescence intensity and increasing order of absorbance at 241 nm. Some regular relationships exist between the molecular structures of xanthene dyes and the photodynamic inactivation of SR membranes.