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ULTRAVIOLET AND γ‐RAY‐INDUCED REACTIONS OF NUCLEIC ACID CONSTITUENTS. REACTIONS OF PURINES WITH AMINES
Author(s) -
Salomon J.,
Elad D.
Publication year - 1974
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1974.tb06469.x
Subject(s) - purine metabolism , nucleic acid , chemistry , ultraviolet , photochemistry , ultraviolet radiation , organic chemistry , biochemistry , radiochemistry , enzyme , materials science , optoelectronics
— Photochemical and γ‐ray‐induced reactions of purines with amines are described. These lead to the appropriate 8‐substituted purines. The photoproducts were obtained in yields of up to 100% by the use of a variety of photosensitizers, including peroxides. A free radical mechanism is proposed for these reactions. Such reactions may be relevant to the problem of the nature of DNA‐protein cross‐links induced by ultraviolet radiation.