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INHIBITION OF 3 H‐THYMIDINE INCORPORATION IN PIG KIDNEY CELLS BY FAR‐RED LIGHT*
Author(s) -
CHEN C. H.,
GORDON S. A.
Publication year - 1972
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1972.tb06229.x
Subject(s) - thymidine , monolayer , kidney , chemistry , biology , biophysics , microbiology and biotechnology , radiochemistry , dna , biochemistry , endocrinology
E xposure of pig kidney cells in monolayer culture to far‐red light (FRL), near 750 nm, was found to increase the incidence of chromatid aberrations and aberrant cells [1]. Dose–response curves for cell populations predominantly in early S reached a maximum at incident energies of ca. 50 mJ cm ‐2 . We show here that the incorporation of tritiated thymidine by the nuclei of pig kidney cells in monolayer also is inhibited by FRL, with a similar dose‐response maximum.