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PHOTOCHEMISTRY OF 1,3‐DIMETHYLTHYMINE IN AQUEOUS SOLUTION *
Author(s) -
Alcántara Raúl,
Wang Shih Yi
Publication year - 1965
Publication title -
photochemistry and photobiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.818
H-Index - 131
eISSN - 1751-1097
pISSN - 0031-8655
DOI - 10.1111/j.1751-1097.1965.tb09761.x
Subject(s) - formaldehyde , formic acid , methylamine , aqueous solution , photochemistry , chemistry , acetic acid , ammonia , thymine , irradiation , nuclear chemistry , dna , organic chemistry , biochemistry , physics , nuclear physics
— This paper reports the isolation and the identification of ammonia, methylamine, 5‐carboxy‐l, 3‐dimethyluracil, acetic acid, formic acid, 5‐formyluracil, and formaldehyde from an aqueous solution of 1,3‐dimethylthymine which was irradiated with 254 mμ light resulting in a decrease of 50 per cent of the original ultraviolet absorbancy. The isolation of 5‐formyl‐l, 3‐dimethyluracil as a major photoproduct indicated the possible photo‐oxidation of the 5‐methyl group of thymine derivatives. The possible presence of an oxidized intermediate in DNA may prove important in radiation biology.