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Neoadjuvant chemoradiotherapy and surgery as treatment for oral maxillary squamous cell carcinoma in a dog
Author(s) -
Mestrinho LA,
Bernardo E,
Niza MMRE,
Lloret A,
Buracco P
Publication year - 2012
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2012.00928.x
Subject(s) - medicine , carboplatin , radiation therapy , basal cell , chemotherapy , chemoradiotherapy , surgery , neoadjuvant therapy , carcinoma , adjuvant radiotherapy , radiology , cisplatin , cancer , breast cancer
A gingival maxillary squamous cell carcinoma was diagnosed in a 12‐year‐old male Yorkshire Terrier. After a complete diagnostic work‐up, including a computed tomography scan, the tumour was staged as T3bN1aM0 and considered non‐resectable at presentation. The combination of neoadjuvant megavoltage radiotherapy and neoadjuvant and adjuvant chemotherapy with carboplatin and doxorubicin decreased the size of the tumour, allowing for surgery. The dog was free from local disease for 421 days after which it was euthanased at the owners' request.