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Diagnostic specificity of an equine influenza blocking ELISA estimated from New South Wales field data from the Australian epidemic in 2007
Author(s) -
Sergeant ESG,
Cowled BD,
Bingham P
Publication year - 2011
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2011.00741.x
Subject(s) - equine influenza , outbreak , virology , nucleoprotein , observational study , virus , veterinary medicine , medicine , serology , immunology , biology , antibody
This observational study was undertaken in order to evaluate the diagnostic specificity of the blocking enzyme‐linked immunosorbent assay (bELISA) for serum antibodies to influenza A virus nucleoprotein during the equine influenza (EI) outbreak response in New South Wales, Australia, in 2007. Using data collected during the outbreak response, bELISA testing data were collated for assumed uninfected horses from areas where EI infection was never recorded. Diagnostic specificity of the bELISA used during the EI response was high, but varied significantly between some regions, although the reason(s) for this variation could not be determined.