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Myofibroblastic fibrosarcoma with multifocal osseous metaplasia at the site of equine influenza vaccination
Author(s) -
Kannegieter NJ,
Schaaf KL,
Lovell DK,
Simon CD,
Stone BM
Publication year - 2010
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2010.00557.x
Subject(s) - fibrosarcoma , medicine , pathology , vaccination , lymph , biopsy
We describe a fibrosarcoma in a 12‐year‐old Quarterhorse × Arabian gelding as a sequela to equine influenza vaccination. Shortly after the second vaccination, swelling at the site was noticed by the owner and it continued to increase in size over the following 6 months. Biopsy of the mass indicated a fibrosarcoma had developed at the vaccination site. It was approximately 20 cm in diameter and elevated well above the level of the skin. There was no clinical evidence of metastases to the lungs or local lymph nodes. Surgical resection of the mass was performed and the wound healed by first and second intention. Histopathological examination and immunohistochemical staining confirmed a myofibroblastic fibrosarcoma with multifocal osseous metaplasia. To the authors' knowledge, this is the first equine case of a vaccine‐associated fibrosarcoma.