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Acute myelomonocytic leukaemia with short‐term spontaneous remission in a cat
Author(s) -
MYLONAKIS ME,
PETANIDES TA,
VALLI VE,
VERNAU W,
KOYTINAS AF,
MICHAEL RS
Publication year - 2008
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2008.00304.x
Subject(s) - leukocytosis , medicine , anorexia , histopathology , acute myelomonocytic leukemia , gastroenterology , pathology , bone marrow , feline leukemia virus , spontaneous remission , tonsil , cats , alternative medicine
A 2‐year‐old, spayed female domestic shorthair cat was referred with a history of anorexia and depression of 1 week duration. On physical examination, the cat was lethargic and febrile, with splenomegaly, anisocoria and ulcerative stomatitis. A complete blood count (CBC) and a biochemistry profile showed leukocytosis, numerous blast cells in the peripheral blood, thrombocytopenia, hyperglobulinaemia and a positive test for feline leukaemia virus antigen. A diagnosis of acute myelomonocytic leukaemia was made on the basis of the results of bone marrow cytology, histopathology, and immunochemistry (CD3, CD79a, lysozyme, and myeloperoxidase) tests. Following an unexpected 1‐month period of clinical and clinicopathological remission without chemotherapy, the cat relapsed and died 1 week later.