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Olfactory esthesioneuroblastoma treated with orthovoltage radiotherapy in a dog
Author(s) -
Ueno H,
Kobayashi Y,
Yamada K
Publication year - 2007
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2007.00149.x
Subject(s) - medicine , esthesioneuroblastoma , nasal cavity , radiation therapy , radiography , nuclear medicine , physical examination , cribriform plate , biopsy , radiology , surgery
A 13‐year‐old neutered female mongrel dog presented with a 1‐year history of stertorous respiration. On computed tomography examination, a mass was demonstrated in the nasal cavity. Open biopsy of the mass was performed and a diagnosis of olfactory esthesioneuroblastoma was made on histological examination. The dog was treated with orthovoltage x‐ray radiation (total dose; 53 Gy given in 14 fractions over an 8 week period). Computed tomography after the twelfth irradiation revealed that tumour size had decreased. Although clinical signs were absent in the 4 months after irradiation, re‐growth of the tumour was detected by radiographic evaluation and histological examination. The dog was again treated with orthovoltage x‐ray radiation (total dose; 30 Gy given in three fractions over a 4‐week period), however, tumour regrowth was again detected 3 months later. Clinical treatment of this tumour type has not been previously reported.