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Hepatocellular carcinoma with secondary abscessation in a cat
Author(s) -
SINGH M,
KROCKENBERGER M,
MARTIN P,
WIMPOLE J,
BEATTY J
Publication year - 2005
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2005.tb11580.x
Subject(s) - echogenicity , hepatocellular carcinoma , pathology , lethargy , differential diagnosis , medicine , gross examination , abdominal ultrasonography , cholestasis , pyometra , anatomy , radiology , gastroenterology , ultrasound , ultrasonography , uterus
A 16‐year‐old castrated male domestic shorthair cat was presented for investigation of weight loss, lethargy, inappetence and polydypsia. On serum biochemical analysis there was evidence of severe hepatocellular damage and cholestasis. Abdominal ultrasonographic examination revealed an irregular lesion of mixed echogenicity in a left hepatic lobe. It was compromised of a hypoechoic periphery surrounding an anechoic central area containing highly echogenic densities with distal acoustic shadowing suggestive of gas formation. On necropsy, the only gross abnormality was a solitary 5 cm×3 cm×3 cm multilobulated mass in the left lateral hepatic lobe, containing foul‐smelling purulent fluid within a thick fibrous wall. Cytological examination of the fluid revealed numerous degenerate neutrophils and large numbers of Gram‐positive sporeforming rods. The histopathological diagnosis was hepatocellular carcinoma with secondary abscessation. The bacterial morphology was consistent with Clostridia sp. Both hepatocellular carcinoma and focal hepatic abscessation are rare in cats. Hepatic abscesses should be included in the differential diagnosis of cats with non‐specific signs, even in the absence of biochemical evidence of a hepatopathy.