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Long QT syndrome in dogs with tick toxicity( Ixodes holocyclus )
Author(s) -
CAMPBELL FE,
ATWELL RB
Publication year - 2002
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2002.tb10963.x
Subject(s) - qt interval , medicine , toxicity , bradycardia , cardiology , ventricular tachycardia , anesthesia , heart rate , sudden cardiac death , long qt syndrome , blood pressure
Objective To evaluate cardiac electrical function in dogs with tick toxicity. Design A prospective clinical investigation of 39 client‐owned dogs treated for naturally occurring tick toxicity. Procedure An ECG was performed on each dog on several occasions; at admission to hospital with tick toxicity, 24 h later, at discharge from hospital when clinically normal and approxi‐mately Results The mean QT interval corrected for heart rate (QTc) was prolonged at admission, 24 h and at discharge compared to the QTc measured 12 months later. T wave morphology was altered in dogs at admission. All other para‐meters were within normal limits. Conclusions The prolonged QTc interval and altered T wave morphology of dogs with tick toxicity reflects delayed cardiac repolarisation and is comparable with long QT syndrome (LQTS) in people who are predisposed to polymor‐phic ventricular tachycardia and sudden death. Resolution of ECG changes lagged behind clinical recovery.