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Successful treatment of invasive nasal cryptococcosis in a ferret
Author(s) -
MALIK R.,
MARTIN P.,
McGILL J.,
MARTIN A.,
LOVE DN
Publication year - 2000
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2000.tb10582.x
Subject(s) - cryptococcosis , itraconazole , debulking , medicine , cryptococcus neoformans , cryptococcus , amphotericin b , lesion , pathology , biology , antifungal , dermatology , microbiology and biotechnology , ovarian cancer , cancer
Invasive cryptococcal rhinitis due to Cryptococcus neoformans var gattii was diagnosed in a castrated, 5‐year‐old, albino ferret with subcutaneous swelling of the nasal bridge. The diagnosis was based on histology, needle aspirate cytology and positive culture on Sabouraud's dextrose agar and birdseed agar. The ferret was successfully treated using a long course of itraconazole (25 to 33 mg orally once daily with food) subsequent to surgical debulking of the lesion, using sequential cryptococcal antigen titre determinations to guide therapy.