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Evaluation of a novel antimicrobial polymer for the control of porcine postweaning colibacillosis
Author(s) -
HAMPSON DJ,
BUDDLE JR,
MELROSE GJH
Publication year - 2000
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.2000.tb10538.x
Subject(s) - antimicrobial , microbiology and biotechnology , biology
Objective To determine whether CHEMYDE RTM polymer has potential for use in the control of porcine postweaning colibacillosis (PWC). Procedure Two experiments were conducted in which 50 young pigs, either receiving CHEMYDE RTM polymer in their food or not, were challenged orally with cultures of beta‐haemolytic Escherichia coli immediately after weaning. Their response in terms of development of diarrhoea, and the extent of colonisation of the intestinal tract by the bacteria was monitored. In a third experiment CHEMYDE RTM polymer was added to the water supply of a group of 15 pigs on a piggery where PWC was an ongoing clinical problem. The response of these pigs was compared with that of pigs vaccinated against PWC or left unmedicated. Results In both experimental infection trials the pigs receiving CHEMYDE RTM polymer showed significantly reduced intestinal colonisation with the challenge strain of E coli , and, in trial 2, significantly less diarrhoea after weaning compared to pigs not receiving CHEMYDE RTM polymer. In the field trial the pigs receiving CHEMYDE RTM polymer had significantly less diarrhoea and required significantly less antibiotic treatment than the other two groups of pigs. Conclusion CHEMYDE RTM polymer has potential for use in the control of PWC.