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Testing the concept of virally vectored immunosterilisation for the control of wild rabbit and fox populations in Australia
Author(s) -
ROBINSON ANTHONY J.,
HOLLAND MICHAEL K.
Publication year - 1995
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1995.tb15335.x
Subject(s) - rabbit (cipher) , biology , virology , veterinary medicine , medicine , computer science , computer security
SUMMARY: Virally vectored immunosterilisation is a concept whereby a gene encoding an antigen from an animal's reproductive system is inserted into a virus and, during infection, stimulates the formation of antibodies to that antigen such that the animal is rendered infertile. There is good evidence that certain proteins from sperm or egg when introduced parenterally will induce infertility. This paper summarises the work of the Cooperative Research Centre for the Biological Control of Vertebrate Pest Populations and reviews progress toward the isolation of the genes for gamete antigens from rabbits and foxes and their introduction into suitable viral vectors as a means of control of these pests in Australia