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Maturation of insulin and glucose responses to normal feeding in foals
Author(s) -
SMYTH GB,
YOUNG DW,
DURAN SH
Publication year - 1993
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1993.tb06103.x
Subject(s) - insulin , endocrinology , biology , medicine
SUMMARY Postprandial insulin and glucose concentrations were measured in 3 Arabian and 3 Thoroughbred foals at 1 day, 1 week, 1 month and 3 months of age. Prefeeding serum Insulin concentrations were similar in foals at 1 day (25.9 ± 5.1 pmol/L), 1 week (32.4 ± 5.8 pmol/L), and 1 month (38.2 + 7.9 pmol/L), but had Increased significantly to 131.0 ± 20.2 pmol/L at 3 months of age (P < 0.05). There was significantly increased serum Insulin secretion after a feed In foals at 3 months of age (P < 0.05) when compared with that at younger ages. Prefeeding serum glucose concentrations ranged from 6.0 ± 0.7 mmol/L at 1 day, to 5.9 ± 0.9 mmol/L at 1 week, 4.9 ± 1.7 mmol/L at 1 month, and 4.4 ± 1.5 mmol/L at 3 months of age. There were lower postprandial glucose concentrations with advancing age. It appeared that there was a period of maturation in pancreatic β‐cell function after birth in foals, which reached adult levels by 3 months of age.