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Antibody responses to avian encephalomyelitis virus vaccines when administered by different routes
Author(s) -
SHAFREN DR,
TANNOCK GA,
GROVES PJ
Publication year - 1992
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1992.tb09888.x
Subject(s) - flock , vaccination , virology , antibody , hatching , virus , encephalomyelitis , biology , medicine , immunology , veterinary medicine , multiple sclerosis , zoology
SUMMARY: Antibody responses to a commercial avian encephalomyelitis virus (AEV) vaccine administered by different routes were measured by an enzyme‐linked immunosorbent assay (ELISA). Responses to single doses of vaccine administered by the ocular route to 10% of a flock were comparable with those obtained when all birds received a single dose in the drinking water. However, ocular vaccination of 5% of the flock resulted in significantly lower responses than those obtained when 10% were vaccinated. Maternal antibody was shown by the ELISA to persist in chickens from vaccinated flocks for up to 21 days after hatching. Day‐old chickens with serum absorbances of <0.3 at 492 nm, as determined by the ELISA, were shown to be susceptible to intracerebral challenge with the neurotropic Van Roekel strain of AEV.