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Cross‐protective immunity and the serological classification system for Bacteroides nodosus
Author(s) -
STEWART DJ,
VAUGHAN JA,
ELLEMAN TC,
HOYNE PA,
BURNS KJ,
DUFTY JH
Publication year - 1991
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1991.tb03128.x
Subject(s) - serology , bacteroides , pilus , biology , vaccination , microbiology and biotechnology , virology , immunity , antibody , cross reactivity , antigen , immune system , cross reactions , immunology , virulence , bacteria , genetics , gene
SUMMARY The relationship between the serological classification system for serogroup B and for serogroup H of Bacteroides nodosus and cross‐protection between subgroups within these serogroups was examined. Protection against ovine footrot following vaccination was achieved against other subgroup strains provided sufficient cross‐reactive antibody was induced by shared pilus antigens. Within serogroup B, better cross‐protection against one subgroup was obtained with a pili vaccine than a whole cell vaccine which correlated with higher pilus antibody titres induced by the former. For serogroup H, a lack of cross‐protection and serological reactivity between subgroups was demonstrated, which indicates that the prototype strain of subgroup H2 should be designated a new serogroup.