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The pathology of Johne's disease in sheep
Author(s) -
CARRIGAN MJ,
SEAMAN JT
Publication year - 1990
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1990.tb07693.x
Subject(s) - paratuberculosis , ileum , enteritis , caecum , jejunum , terminal ileum , pathology , ileitis , breed , biology , gastroenterology , medicine , disease , veterinary medicine , mycobacterium , crohn's disease , zoology , tuberculosis
SUMMARY The clinical, gross and histopathological findings in 50 sheep affected with Johne's disease are described. Clinically 90% were emaciated and 20% showed severe diarrhoea. On necropsy there was thickening of the walls of the intestines, particularly of the ileum, caecum and less frequently the jejunum, but in 36% of sheep the changes were only mild. Histologically there was a granulomatous enteritis, typhlitis and colitis, with the most severe changes in the terminal ileum. High numbers of acid‐fast organisms were present in the terminal ileum in over 70% of sheep. Mycobacterium paratuberculosis was cultured from only 8% of the sheep examined.

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