Premium
Plasma and liver concentrations of aP‐tocopherol in weaner sheep after vitamin E supplementation
Author(s) -
DONCON GH,
STEELE P
Publication year - 1988
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1988.tb14460.x
Subject(s) - tocopherol , pasture , vitamin e , zoology , oral administration , plasma concentration , oral dose , chemistry , vitamin , blood plasma , biology , endocrinology , biochemistry , antioxidant , agronomy
SUMMARY: changes in the plasma and liver concentrations of aP‐tocopherol in sheep kept in an animal house, grazed on pasture, grazed on pasture and fed an oatllupin grain supplement, or grazed on toxic lupin stubble were monitored following no, oral or intramuscular administration of aP‐tocopherol. It was concluded that intramuscular administration was most effective because it caused longer periods of elevated plasma aP. tocopherol concentrations in most situations investigated and consistently higher concentrations of aP‐tocopherol in the liver, compared to oral administration. The dose rates of aP‐tocopherol given, the vehicle for ap‐tocopherol in the injectable preparation, the different diets consumed and the concurrent occurrence of lupinosis all influenced the results. In spite of this a significant positive correlation existed between the terminal liver and plasma aP‐tocopherol concentrations.