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Adverse reaction to procaine penicillin G in horses
Author(s) -
NIELSEN IL,
JACOBS KA,
HUNTINGTON PJ,
CHAPMAN CB,
LLOYD KC
Publication year - 1988
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1988.tb14296.x
Subject(s) - procaine , penicillin , medicine , adverse effect , horse , anesthesia , intramuscular injection , anaphylaxis , surgery , antibiotics , allergy , immunology , biology , microbiology and biotechnology , paleontology
SUMMARY: Adverse reactions to intramuscular injections of procaine penicillin G are reported in 11 horses, five of which died. The clinical findings are presented and suggest central nervous involvement in most cases. Post mortem findings in one horse were consistent with anaphylaxis whereas in other cases the clinical findings, duration of treatment, speed of onset and subsequent completion of treatment supports diagnosis of an acute procaine toxicity syndrome.