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Successful long term treatment of a dog with psychomotor seizures using carbamazepine
Author(s) -
HOLLAND CT
Publication year - 1988
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1988.tb14280.x
Subject(s) - carbamazepine , epilepsy , psychomotor learning , medicine , anesthesia , anticonvulsant , electroencephalography , psychiatry , cognition
SUMMARY: Psychomotor seizures (temporal lobe epilepsy) were diagnosed in a dog based on history, clinical findings and electroencephalography. Long‐term seizure control was achieved with carbamazepine, despite serum drug concentrations which were low to unmeasurable. It is suggested that serum levels of carbamazepine are not a useful guide to clinical efficacy in the dog, that an unmeasured metabolite of carbamazepine may account for the anti‐convulsant activity and that carbamazepine may be potentially useful in treating certain canine seizure disorders.