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Vaccination as a possible means of preventing lantana poisoning
Author(s) -
STEWART C.,
LAMBERTON JA,
FAIRCLOUGHS RJ,
PASS MA
Publication year - 1988
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1988.tb14262.x
Subject(s) - lantana camara , lantana , vaccination , adjuvant , biology , medicine , traditional medicine , immunology , botany
SUMMARY: The toxic triterpene acids lantadene A and lantadene B were isolated from Lantana camara and conjugated to bovine serum albumen or haemocyanin. The conjugates were emulsified with complete Freund's adjuvant and injected into sheep and cattle. Vaccinated animals produced antibodies against the toxic compounds. Cholestasis was less severe in vaccinated than in non‐vaccinated sheep challenged with a toxic dose of lantana. The results indicated a mild protective effect of vaccination against the hepatotoxic effects of lantana toxins.