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Experimentally induced lactic acidosis in the goat
Author(s) -
CAO G R,
ENGLISH P B,
FILIPPICH L J,
INGLIS S.
Publication year - 1987
Publication title -
australian veterinary journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.382
H-Index - 59
eISSN - 1751-0813
pISSN - 0005-0423
DOI - 10.1111/j.1751-0813.1987.tb09605.x
Subject(s) - lactic acid , lactic acidosis , acidosis , metabolic acidosis , bicarbonate , alkalosis , metabolic alkalosis , chemistry , medicine , acid–base reaction , zoology , endocrinology , biochemistry , biology , bacteria , genetics , organic chemistry
SUMMARY Lactic acidosis was produced experimentally twice in each of 4 adult, female goats, by giving sucrose orally at the rate of 18 g/kg bodyweight. Changes in pH, osmolality, lactic acid concentration, and other constituents in ruminal fluid, plasma and blood were monitored over a period of 48 h. Also changes in urinary pH and sediment were examined. To ameliorate the metabolic disturbance, calcium hydroxide and bicarbonate treatment was employed after the 24 h samples had been collected and their acid‐base status determined. A feature of the disturbance in the goats was that a metabolic alkalosis preceded the onset of lactic acidosis.